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Glossary Term

Federalwide Assurance (FWA)

An institution's written commitment to OHRP to comply with 45 CFR 46 for federally supported human-subjects research.

An institution that conducts non-exempt human-subjects research supported by HHS must hold an active Federalwide Assurance. The FWA designates one or more IRBs to review the institution's research and affirms the institution's commitment to ethical principles such as those in the Belmont Report.

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